Permeation through an open channel: Poisson-Nernst-Planck theory of a synthetic ionic channel
نویسندگان
چکیده
منابع مشابه
Solutions to a nonlinear Poisson-Nernst-Planck system in an ionic channel
A limiting one-dimensional Poisson-Nernst-Planck (PNP) equations is considered, when the three-dimensional domain shrinks to a line segment, to describe the flows of positively and negatively charged ions through open ion channel. The new model comprises the usual drift diffusion terms and takes into account for each phase, the bulk velocity defined by (4) including the water bath for ions (see...
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Permeation of ions from one electrolytic solution to another, through a protein channel, is a biological process of considerable importance. Permeation occurs on a time scale of micro- to milliseconds, far longer than the femtosecond time scales of atomic motion. Direct simulations of atomic dynamics are not yet possible for such long-time scales; thus, averaging is unavoidable. The question is...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1997
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(97)78650-8